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Literature summary for 1.1.1.35 extracted from

  • Toma, C.; Koizumi, N.; Kakita, T.; Yamaguchi, T.; Hermawan, I.; Higa, N.; Yamashiro, T.
    Leptospiral 3-hydroxyacyl-CoA dehydrogenase as an early urinary biomarker of leptospirosis (2018), Heliyon, 4, e00616 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.1.35

Application

Application Comment Organism
medicine the leptospiral enzyme is an early urinary biomarker of leptospirosis Leptospira interrogans

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21-AI cells Leptospira interrogans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-oxoacyl-CoA + NADH + H+ Leptospira interrogans
-
 (S)-3-hydroxyacyl-CoA + NAD+
-
 ?
3-oxoacyl-CoA + NADH + H+ Leptospira interrogans UP-MMC-NIID
-
 (S)-3-hydroxyacyl-CoA + NAD+
-
 ?

Organism

Organism UniProt Comment Textmining
Leptospira interrogans
-
 serovar Manilae
-
Leptospira interrogans UP-MMC-NIID
-
 serovar Manilae
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-oxoacyl-CoA + NADH + H+
-
 Leptospira interrogans (S)-3-hydroxyacyl-CoA + NAD+
-
 ?
3-oxoacyl-CoA + NADH + H+
-
 Leptospira interrogans UP-MMC-NIID (S)-3-hydroxyacyl-CoA + NAD+
-
 ?

Subunits

Subunits Comment Organism
? x * 52000, His-tagged recombinant enzyme, SDS-PAGE Leptospira interrogans

Synonyms

Synonyms Comment Organism
3-HADH
-
 Leptospira interrogans

Cofactor

Cofactor Comment Organism Structure
NADH
-
 Leptospira interrogans