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Literature summary for 1.1.1.284 extracted from

  • Hussain, A.; Yun, B.W.; Kim, J.H.; Gupta, K.J.; Hyung, N.I.; Loake, G.J.
    Novel and conserved functions of S-nitrosoglutathione reductase in tomato (2019), J. Exp. Bot., 70, 4877-4886 .
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information enzyme SlGSNOR knockout by gene silencing with RNAi using Agrobacterium tumefaciens transfection method. The accumulation of SlGSNOR1 transcripts is tightly regulated in tomato MicroTom and a significant reduction in its expression leads to lethality, as SlGSNOR-RNAi lines with greater than about 60% reduction in SlGSNOR1 expression are not viable. Both SlGSNOR-RNAi and SlGSNOR-overexpressing(OE) lines convey significant effects on the overall development of tomato plants, ranging from seed germination to fruiting and net yield per plant. Reduced GSNOR expression in SlGSNOR-RNAi lines drastically affects seed development and reduces the number of seeds produced in the fruits of the resulting transgenic plants, phenotype, overview. SlGSNOR-RNAi plants also show faster germination as compared with wild-type and SlGSNOR-OE plants on either MS medium or soil, and show the appearance of fresh green tissues at least 1 d before the wild-type and overexpressing plants Solanum lycopersicum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-nitrosoglutathione + NADPH + H+ Solanum lycopersicum
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GSSG + ammonia + NADP+
-
ir

Organism

Organism UniProt Comment Textmining
Solanum lycopersicum D2Y3F4 var. MicroTom
-

Source Tissue

Source Tissue Comment Organism Textmining
fruit
-
Solanum lycopersicum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-nitrosoglutathione + NADPH + H+
-
Solanum lycopersicum GSSG + ammonia + NADP+
-
ir

Synonyms

Synonyms Comment Organism
GSNOR
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Solanum lycopersicum
S-nitrosoglutathione reductase
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Solanum lycopersicum
SlGSNOR
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Solanum lycopersicum

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Solanum lycopersicum

General Information

General Information Comment Organism
malfunction depletion of GSNOR function impacts tomato (Solanum lycopersicum. L) fruit development. Thus, reduction of GSNOR expression through RNAi modulated both fruit formation and yield, establishing another function for GSNOR. Further, depletion of Solanum lycopersicum GSNOR (SlGSNOR) additionally impacted a number of other developmental processes, including seed development, which also has not been previously linked with GSNOR activity. Depletion of GSNOR function does not influence root development in tomato. Reduction of GSNOR transcript abundance compromises plant immunity. Overexpression of SlGSNOR promotes resistance to bacterial pathogens, such as Pseudomonas syringae pv. tomato DC3000 (PstDC3000) Solanum lycopersicum
physiological function nitric oxide (NO) is emerging as a key signalling molecule in plants. The chief mechanism for the transfer of NO bioactivity is thought to be S-nitrosylation, the addition of an NO moiety to a protein cysteine thiol to form an S-nitrosothiol (SNO). The enzyme S-nitrosoglutathione reductase (GSNOR) indirectly controls the total levels of cellular S-nitrosylation, by depleting S-nitrosoglutathione (GSNO), the major cellular NO donor. SlGSNOR regulates seed devlopment, fruit production, and flower development, overview Solanum lycopersicum