Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
tropinone + NADPH + H+ | Hyoscyamus muticus | tropinone reductase I | tropine + NADP+ | - |
? | |
tropinone + NADPH + H+ | Hyoscyamus senecionis | tropinone reductase I | tropine + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Hyoscyamus muticus | - |
- |
- |
Hyoscyamus senecionis | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leaf | hyoscyamine is the main tropane alkaloid of the leaf and root of Hyoscyamus muticus | Hyoscyamus muticus | - |
leaf | scopolamine is the main tropane alkaloid compound in Hyoscyamus senecionis leaves | Hyoscyamus senecionis | - |
root | hyoscyamine is the main tropane alkaloid of the leaf and root of Hyoscyamus muticus | Hyoscyamus muticus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
tropinone + NADPH + H+ | tropinone reductase I | Hyoscyamus muticus | tropine + NADP+ | - |
? | |
tropinone + NADPH + H+ | tropinone reductase I | Hyoscyamus senecionis | tropine + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
tropinone reductase I | - |
Hyoscyamus muticus |
tropinone reductase I | - |
Hyoscyamus senecionis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Hyoscyamus muticus | |
NADPH | - |
Hyoscyamus senecionis |
General Information | Comment | Organism |
---|---|---|
metabolism | tropinone reductase I is involved in the scopolamine biosynthetic pathway, overview. Hyoscyamine is the main tropane alkaloid of the leaf and root of Hyoscyamus muticus. Higher amounts of littorine as an intermediate compound in the pathway, and 3'-hydroxylittorine are accumulated in roots than in other organs | Hyoscyamus muticus |
metabolism | tropinone reductase I is involved in the scopolamine biosynthetic pathway, overview. Scopolamine is the main tropane alkaloid compound in Hyoscyamus senecionis leaves. Higher amounts of littorine as an intermediate compound in the pathway, and 3'-hydroxylittorine are accumulated in roots than in other organs | Hyoscyamus senecionis |