Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | upregulation of the enzyme by homocysteine in type II alveolar epithelial cells, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
aldose + NADPH + H+ | Homo sapiens | upregulation of the enzyme by homocysteine in type II alveolar epithelial cells can lead to cell damage and pulmonary disease, overview | alditol + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P15121 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-549 cell | type II alveolar epithelial cell line, AR expression analysis | Homo sapiens | - |
lung | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
aldose + NADPH + H+ | - |
Homo sapiens | alditol + NADP+ | - |
? | |
aldose + NADPH + H+ | upregulation of the enzyme by homocysteine in type II alveolar epithelial cells can lead to cell damage and pulmonary disease, overview | Homo sapiens | alditol + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AKR1B1 | - |
Homo sapiens |
aldose reductase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Homo sapiens |