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Literature summary for 1.1.1.202 extracted from

  • Hao, J.; Wang, W.; Tian, J.; Li, J.; Liu, D.
    Decrease of 3-hydroxypropionaldehyde accumulation in 1,3-propanediol production by over-expressing dhaT gene in Klebsiella pneumoniae TUAC01 (2008), J. Ind. Microbiol. Biotechnol., 35, 735-741.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene dhaT, DNA and amino acid sequence determination and analysis, sequence comparisons Klebsiella pneumoniae

Protein Variants

Protein Variants Comment Organism
additional information engineering of a strain for optimized elimination of 3-hydroxypropionaldehyde, an inhibitory intermediary metabolite in the 1,3-propanediol synthesis pathway, from the broth during fermentation process of raw material required for the synthesis of polytrimethylene terephthalate and other polyester fibers, overview Klebsiella pneumoniae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-hydroxypropanal + NADH + H+ Klebsiella pneumoniae 3-hydroxypropionaldehyde is an inhibitory intermediary metabolite in the 1,3-propanediol synthesis pathway during fermentation of raw material required for the synthesis of polytrimethylene terephthalate and other polyester fibers, accumulation of 3-hydroxypropanal in broth causes an irreversible cessation of the fermentation process propane-1,3-diol + NAD+
-
r
3-hydroxypropanal + NADH + H+ Klebsiella pneumoniae TUAC01 3-hydroxypropionaldehyde is an inhibitory intermediary metabolite in the 1,3-propanediol synthesis pathway during fermentation of raw material required for the synthesis of polytrimethylene terephthalate and other polyester fibers, accumulation of 3-hydroxypropanal in broth causes an irreversible cessation of the fermentation process propane-1,3-diol + NAD+
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r

Organism

Organism UniProt Comment Textmining
Klebsiella pneumoniae A3RL85 gene dhaT
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Klebsiella pneumoniae TUAC01 A3RL85 gene dhaT
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-hydroxypropanal + NADH + H+
-
Klebsiella pneumoniae propane-1,3-diol + NAD+
-
r
3-hydroxypropanal + NADH + H+ 3-hydroxypropionaldehyde is an inhibitory intermediary metabolite in the 1,3-propanediol synthesis pathway during fermentation of raw material required for the synthesis of polytrimethylene terephthalate and other polyester fibers, accumulation of 3-hydroxypropanal in broth causes an irreversible cessation of the fermentation process Klebsiella pneumoniae propane-1,3-diol + NAD+
-
r
3-hydroxypropanal + NADH + H+
-
Klebsiella pneumoniae TUAC01 propane-1,3-diol + NAD+
-
r
3-hydroxypropanal + NADH + H+ 3-hydroxypropionaldehyde is an inhibitory intermediary metabolite in the 1,3-propanediol synthesis pathway during fermentation of raw material required for the synthesis of polytrimethylene terephthalate and other polyester fibers, accumulation of 3-hydroxypropanal in broth causes an irreversible cessation of the fermentation process Klebsiella pneumoniae TUAC01 propane-1,3-diol + NAD+
-
r

Synonyms

Synonyms Comment Organism
PDOR
-
Klebsiella pneumoniae

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Klebsiella pneumoniae
NADH
-
Klebsiella pneumoniae