Literature summary for 1.1.1.184 extracted from

Zhang, X.J.; Zhou, R.; Wu, D.; Tang, Y.Q.; Wang, M.Y.; Liu, Z.Q.; Zheng, Y.G.
Efficient production of an ezetimibe intermediate using carbonyl reductase coupled with glucose dehydrogenase (2021), Biotechnol. Prog., 37, e3068 .

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Cloned(Commentary)

Cloned (Comment)	Organism
co-expressed with glucose dehydrogenase from Exiguobacterium sibiricum in Escherichia coli BL21 (DE3) cells	Lentilactobacillus kefiri

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
(4S)-3-[5-(4-fluorophenyl)-1,5-dioxopentyl]-4-phenyl-2-oxazolidinone + NADPH + H+	Lentilactobacillus kefiri	99.1% conversion	(4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one + NADP+	-	?

Organism

Organism	UniProt	Comment	Textmining
Lentilactobacillus kefiri	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(4S)-3-[5-(4-fluorophenyl)-1,5-dioxopentyl]-4-phenyl-2-oxazolidinone + NADPH + H+	99.1% conversion	Lentilactobacillus kefiri	(4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one + NADP+	-	?

Synonyms

Synonyms	Comment	Organism
CR125	-	Lentilactobacillus kefiri

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Release 2023.1 (January 2023)