Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | treatment of colorectal cancer cells with 5-aza-2'-deoxycytidine, 5 mM sodium butyrate or 5 mM valproic acid induces an increase in 15-PGDH protein expression | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | histone deacetylase 2 and the transcriptional regulator Snail play a central role in the suppression of 15-PGDH expression | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
colorectal cancer cell | - |
Homo sapiens | - |
HT-29 cell | - |
Homo sapiens | - |
LS174T cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
15-PGDH | - |
Homo sapiens |
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | dependent on | Homo sapiens |