Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lung | - |
Homo sapiens | - |
non-small cell lung cancer cell | reduced expression of 15-PGDH occurrs in tumor cells and is paralleled by decreased 15-PGDH activity in tumors | Homo sapiens | - |
non-small cell lung cancer cell | the amount of 15-PGDH is frequently decreased in NSCLC cells compared with adjacent normal lung | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
prostaglandin E1 + NAD+ | - |
Homo sapiens | 15-ketoprostaglandin E1 + NADH + H+ | - |
? | |
prostaglandin E2 + NAD+ | - |
Homo sapiens | 15-ketoprostaglandin E2 + NADH + H+ | - |
? | |
prostaglandin F2alpha + NAD+ | - |
Homo sapiens | 15-ketoprostaglandin F2alpha + NADH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
15-PGDH | - |
Homo sapiens |
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | dependent on | Homo sapiens |