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Literature summary for extracted from

  • Beaudoin, F.; Wu, X.; Li, F.; Haslam, R.P.; Markham, J.E.; Zheng, H.; Napier, J.A.; Kunst, L.
    Functional characterization of the Arabidopsis beta-ketoacyl-coenzyme A reductase candidates of the fatty acid elongase (2009), Plant Physiol., 150, 1174-1191.
    View publication on PubMedView publication on EuropePMC


Cloned (Comment) Organism
YFP-KCR1 and CFP-KCR2 fusion constructs transiently expressed in tobacco under the control of the 35S promoter or in Arabidopsis. KCR1 and KCR2 expressed in the yeast ybr159DELTA mutant Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information insertional mutants in KCR1 and KCR2 Arabidopsis thaliana


Inhibitors Comment Organism Structure
RNAi suppresses KCR activity, which results in a reduction of cuticular wax load and affects very-long-chain fatty acid composition of sphingolipids, seed triacylglycerols, and root glycerolipids. RNAi-suppressed Arabidopsis KCR1 plants display fused vegetative and reproductive organs, an abnormal root morphology and have abnormal trichome and epidermal cell morphology Arabidopsis thaliana


Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum KCR1 and KCR2 Arabidopsis thaliana 5783

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
sequence analysis, KCR2 Arabidopsis thaliana


Organism UniProt Comment Textmining
Arabidopsis thaliana

Source Tissue

Source Tissue Comment Organism Textmining
embryo KCR1 and KCR2 Arabidopsis thaliana
flower KCR1 and KCR2 Arabidopsis thaliana
inflorescence KCR1 and KCR2 present in inflorescence stem Arabidopsis thaliana
leaf KCR1 and KCR2 Arabidopsis thaliana
root only KCR1 Arabidopsis thaliana
silique KCR1 and KCR2 Arabidopsis thaliana


Synonyms Comment Organism
beta-ketoacyl reductase
Arabidopsis thaliana
Arabidopsis thaliana
Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction loss of KCR1 function results in embryo lethality, which cannot be rescued by KCR2 expression using the KCR1 promoter. Disruption of the KCR2 gene has no obvious phenotypic effect Arabidopsis thaliana
physiological function only KCR1 is a functional KCR isoform involved in microsomal fatty acid elongation Arabidopsis thaliana