Ligand (+/-)-1-(1H-imidazol-1-yl)-4-(4-iodophenyl)-2-butanol hydrochloride
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Basic Ligand Information
C13H16ClIN2O
(+/-)-1-(1H-imidazol-1-yl)-4-(4-iodophenyl)-2-butanol hydrochloride
GYKICXKDQTWYIQ-UHFFFAOYSA-N
(+-)-1-(1H-imidazol-1-yl)-4-(4-iodophenyl)-2-butanol hydrochloride
Roles as Enzyme Ligand
Inhibitor in Enzyme-catalyzed Reactions (2 results)
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Enzyme Kinetic Parameters
IC50 Value (3 results)
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0.00006
-
IC50: 0.00006 mM
0.06
-
pH 7.4, 37°C, spleen isozyme HO-1
1.8
-
pH 7.4, 37°C, brain isozyme HO-2
References & Links
Literature References (1)
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Heme oxygenase inhibition by 2-oxy-substituted 1-(1H-imidazol-1-yl)-4-phenylbutanes: Effect of halogen substitution in the phenyl ring
2007
Roman, G.; Riley, J.G.; Vlahakis, J.Z.; Kinobe, R.T.; Brien, J.F.; Nakatsu, K.; Szarek, W.A.
Bioorg. Med. Chem.
15
3225-3234
Links to other databases for (+/-)-1-(1H-imidazol-1-yl)-4-(4-iodophenyl)-2-butanol hydrochloride