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Information on EC 4.1.1.123 - phenyl-phosphate phosphatase/carboxylase

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EC Tree
     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.123 phenyl-phosphate phosphatase/carboxylase
IUBMB Comments
The enzyme, characterized from the bacterium Thauera aromatica, participates in an anaerobic phenol degradation pathway. It catalyses the para dephosphorylation and carboxylation of phenylphosphate to 4-hydroxybenzoate. The enzyme from Thauera aromatica consists of four different subunits and requires K+ and a divalent metal cation (Mg2+ or Mn2+) for activity. It is strongly inhibited by oxygen.
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The expected taxonomic range for this enzyme is: Thauera aromatica
Synonyms
phenyl phosphate carboxylase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4-hydroxybenzoate + phosphate = phenyl phosphate + CO2 + H2O
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