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Information on EC 2.5.1.116 - homogentisate geranylgeranyltransferase

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EC Tree
IUBMB Comments
Requires Mg2+ for activity. Involved in the biosynthesis of the vitamin E, tocotrienols. While the enzyme from the bacterium Synechocystis PCC 6803 has higher activity with phytyl diphosphate (EC 2.5.1.115, homogentisate phytyltransferase), the enzymes from barley, rice and wheat have only a low activity with that substrate .
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
homogentisate geranylgeranyltransferase, homogentisic acid geranylgeranyl transferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
geranylgeranyl diphosphate + homogentisate = diphosphate + 6-geranylgeranyl-2-methylbenzene-1,4-diol + CO2
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