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EC Tree
The enzyme appears in viruses and cellular organisms
Synonyms
UDP-glucose:nicotinic acid-N-glucosyltransferase, uridine diphosphoglucose-nicotinate N-glucosyltransferase,
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UDP-glucose:nicotinic acid-N-glucosyltransferase
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uridine diphosphoglucose-nicotinate N-glucosyltransferase
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UDP-glucose + nicotinate = UDP + N-glucosylnicotinate
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hexosyl group transfer
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UDP-glucose:nicotinate N-glucosyltransferase
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UDP-glucose + catechol
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UDP-glucose + nicotinate
UDP + N-glucosylnicotinate
UDP-glucose + nicotinic acid methyl ester
UDP + N-glucosylnicotinic acid methyl ester
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UDP-glucose + vanillic acid
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UDP-glucose + vanillin
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UDPglucose + nicotinate
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the reversible glucosyltransferase reaction provides free nicotinate for the synthesis of NAD+ and NADP+ in pyridine nucleotide cycle
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UDP-glucose + nicotinate
UDP + N-glucosylnicotinate
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UDP-glucose + nicotinate
UDP + N-glucosylnicotinate
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high specificity for UDPglucose as glucosyl donor
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r
UDP-glucose + nicotinate
UDP + N-glucosylnicotinate
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UDPglucose + nicotinate
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the reversible glucosyltransferase reaction provides free nicotinate for the synthesis of NAD+ and NADP+ in pyridine nucleotide cycle
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additional information
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no requirement for divalent cations
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6-Hydroxynicotinic acid
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73% inhibition at 1 mM
benzoic acid
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88% inhibition at 1 mM
Isonicotinic acid
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98% inhibition at 1 mM
N1-methylnicotinamide
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33% inhibition at 1 mM
nicotinic acid N-oxide
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31% inhibition at 1 mM
p-chloromercuribenzoate
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Salicylamide
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30% inhibition at 1 mM
UTP
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33% inhibition at 1 mM
Zn2+
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at 1 mM
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0.17 - 0.22
nicotinic acid
0.17
nicotinic acid
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1.2
UDPglucose
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additional information
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5 - 11
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at pH 5 nearly inactive, at pH 11 about 50% of activity maximum
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XD-6, inducible enzyme by culture with niacin
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brenda
Hoffm., parsley
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brenda
HH258 and F81
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brenda
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brenda
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brenda
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brenda
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heterotrophic
brenda
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brenda
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brenda
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A0A7C9DZQ7_OPUST
148
0
16419
TrEMBL
Secretory Pathway (Reliability: 5)
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monomer
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1 * 46000, SDS-PAGE
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partial
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Taguchi, H.; Sasatani, K.; Nishitani, H.; Okumura, K.
Finding of UDP-glucose:nicotinic acid-N-glucosyltransferase activity in cultured tobacco cells and its properties
Biosci. Biotechnol. Biochem.
61
720-722
1997
Nicotiana tabacum
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brenda
Kster, S.; Upmeier, B.; Komossa, D.; Barz, W.
Nicotinic acid conjugation in plants and plant cell cultures of potato (Solanum tuberosum)
Z. Naturforsch. C
44c
623-628
1989
Solanum tuberosum
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brenda
Upmeier, B.; Thomzik, J.E.; Barz, W.
Enzymatic studies on the reversible synthesis of nicotinic acid-N-glucoside in heterotrophic parsley cell suspension cultures
Z. Naturforsch. C
43c
835-842
1988
Petroselinum crispum
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brenda
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