Disease on EC 2.1.1.8 - histamine N-methyltransferase
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Adenoma
Decreased histamine catabolism in the colonic mucosa of patients with colonic adenoma.
Alzheimer Disease
No association between histamine N-methyltransferase functional polymorphism Thr105Ile and Alzheimer's disease.
Amyotrophic Lateral Sclerosis
Determining the Effect of the HNMT, STK39, and NMD3 Polymorphisms on the Incidence of Parkinson's Disease, Amyotrophic Lateral Sclerosis, and Multiple System Atrophy in Chinese Populations.
Asthma
Association of the histamine N-methyltransferase C314T (Thr105Ile) polymorphism with atopic dermatitis in Caucasian children.
Asthma
Genetic variation within the histamine pathway among patients with asthma - a pilot study.
Asthma
Histamine N-methyltransferase pharmacogenetics: association of a common functional polymorphism with asthma.
Asthma
Lack of association between atopic asthma and polymorphisms of the histamine H1 receptor, histamine H2 receptor, and histamine N-methyltransferase genes.
Asthma
Lack of association of histamine-N-methyltransferase (HNMT) polymorphisms with asthma in the Indian population.
Asthma
No association between histamine N-methyltransferase functional polymorphism Thr105Ile and Alzheimer's disease.
Asthma
No association of histamine- N-methyltransferase polymorphism with asthma or bronchial hyperresponsiveness in two German pediatric populations.
Asthma
Polymorphisms of histamine-metabolizing enzymes and clinical manifestations of asthma and allergic rhinitis.
Asthma
Polymorphisms of two histamine-metabolizing enzymes genes and childhood allergic asthma: a case control study.
Asthma
Theoretical 3D model of histamine N-methyltransferase: insights into the effects of a genetic polymorphism on enzymatic activity and thermal stability.
Breast Neoplasms
Associations of polymorphisms in histidine decarboxylase, histamine N-methyltransferase and histamine receptor H3 genes with breast cancer.
Chronic Urticaria
Histamine N-methyltransferase 939A>G polymorphism affects mRNA stability in patients with acetylsalicylic acid-intolerant chronic urticaria.
Colitis, Ulcerative
Severity of ulcerative colitis is associated with a polymorphism at diamine oxidase gene but not at histamine N-methyltransferase gene.
Cough
Enzymatic modulation of bronchoconstriction, gland secretion, plasma extravasation and cough.
Cystic Fibrosis
Diets high in heat-treated soybean meal reduce the histamine-induced epithelial response in the colon of weaned piglets and increase epithelial catabolism of histamine.
Decompression Sickness
Comparison of the acyl chain specificities of human myristoyl-CoA synthetase and human myristoyl-CoA:protein N-myristoyltransferase.
Dermatitis, Atopic
Association of the histamine N-methyltransferase C314T (Thr105Ile) polymorphism with atopic dermatitis in Caucasian children.
Dermatitis, Atopic
Involvement of human histamine N-methyltransferase gene polymorphisms in susceptibility to atopic dermatitis in korean children.
Dermatitis, Atopic
MicroRNA-223 is involved in the pathogenesis of atopic dermatitis by affecting histamine-N-methyltransferase.
Down Syndrome
Human brain cytosolic histamine-N-methyltransferase is decreased in Down syndrome and increased in Pick's disease.
Duodenal Ulcer
C314T polymorphism in histamine N-methyltransferase gene and susceptibility to duodenal ulcer in Chinese population.
Duodenal Ulcer
Gastric mucosal histamine and histamine methyltransferase in patients with duodenal ulcer.
Duodenal Ulcer
Gastric mucosal histamine and histamine methytltransferase in patients with duodenal ulcer.
Duodenal Ulcer
Histamine and duodenal ulcer: effect of omeprazole on gastric histamine in patients with duodenal ulcer.
Duodenal Ulcer
Histamine and peptic ulcer disease: histamine methyltransferase activity in gastric mucosa of control subjects and duodenal ulcer patients before and after surgical treatment.
Duodenal Ulcer
[Histamine and its role in peptic gastric diseases: the discovery of histamine-H2-receptor antagonists]
Epilepsy, Reflex
Metoprine induced behavioral modifications and brain regional histamine increase in WAG/Rij and Wistar rats.
Essential Tremor
Histamine N-methyltransferase Thr105Ile is not associated with Parkinson's disease or essential tremor.
Essential Tremor
No association between histamine N-methyltransferase functional polymorphism Thr105Ile and Alzheimer's disease.
Essential Tremor
The nonsynonymous Thr105Ile polymorphism of the histamine N-methyltransferase is associated to the risk of developing essential tremor.
Food Hypersensitivity
Both catabolic pathways of histamine via histamine-N-methyltransferase and diamine oxidase are diminished in the colonic mucosa of patients with food allergy.
Heart Failure
Associations of Polymorphisms in HRH2, HRH3, DAO, and HNMT Genes with Risk of Chronic Heart Failure.
Hepatitis
Effect of amodiaquine, a histamine N-methyltransferase inhibitor, on, Propionibacterium acnes and lipopolysaccharide-induced hepatitis in mice.
histamine n-methyltransferase deficiency
Histamine N-methyltransferase regulates aggression and the sleep-wake cycle.
histamine n-methyltransferase deficiency
[Analysis of brain histamine clearance using genetically engineered mice].
Hydronephrosis
Induction of histamine methyltransferase during experimental hydronephrosis: a mechanism of adaptation for histamine homeostasis in rabbit kidney.
Hypersensitivity
Association of diamine oxidase and histamine N-methyltransferase polymorphisms with presence of migraine in a group of Mexican mothers of children with allergies.
Hypersensitivity
Expression of histidine decarboxylase messenger RNA and histamine N-methyltransferase messenger RNA in nasal allergy.
Hypersensitivity
Histamine N-methyltransferase modulates histamine- and antigen-induced bronchoconstriction in guinea pigs in vivo.
Hypertension
Histamine, histidine decarboxylase and histamine-N-methyltransferase in brain areas of spontaneously hypertensive rats.
Hypotension
Cardiac and regional haemodynamic effects of histamine N-methyltransferase inhibitor metoprine in haemorrhage-shocked rats.
Hypotension
Endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats--studies with histamine N-methyltransferase inhibitor SKF 91488.
Hypotension
Endogenous central histamine-induced reversal of critical hemorrhagic hypotension in rats: studies with L-histidine.
Hypotension
Influence of SKF 91488, histamine N-methyltransferase inhibitor, on the central cardiovascular regulation during controlled, stepwise hemorrhagic hypotension in rats.
Hypotension
Involvement of arginine vasopressin in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats.
Hypotension
Involvement of proopiomenalocortin-derived peptides in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats.
Hypotension
Involvement of the renin-angiotensin system in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats.
Hypotension
Involvement of the sympathetic nervous system in the reversal of critical haemorrhagic hypotension by endogenous central histamine in rats.
Infections
Airway hyperresponsiveness to histamine in mycoplasmal infection: role of histamine N-methyltransferase.
Infections
Viral respiratory infection causes airway hyperresponsiveness and decreases histamine N-methyltransferase activity in guinea pigs.
Intellectual Disability
Adult male patient with severe intellectual disability caused by a homozygous mutation in the HNMT gene.
Intellectual Disability
Leucine 208 in human histamine N-methyltransferase emerges as a hotspot for protein stability rationalizing the role of the L208P variant in intellectual disability.
Intellectual Disability
Mutations in the histamine N-methyltransferase gene, HNMT, are associated with nonsyndromic autosomal recessive intellectual disability.
Intestinal Diseases
Histamine N-methyltransferase and diamine oxidase gene polymorphisms in patients with inflammatory and neoplastic intestinal diseases.
Leukemia, Erythroblastic, Acute
A comparative analysis of the kinetic mechanism and peptide substrate specificity of human and Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase.
Migraine Disorders
Association of diamine oxidase and histamine N-methyltransferase polymorphisms with presence of migraine in a group of Mexican mothers of children with allergies.
Movement Disorders
The nonsynonymous Thr105Ile polymorphism of the histamine N-methyltransferase is associated to the risk of developing essential tremor.
Multiple Sclerosis
Histamine and histamine-N-methyltransferase in the CSF of patients with multiple sclerosis.
Multiple System Atrophy
Determining the Effect of the HNMT, STK39, and NMD3 Polymorphisms on the Incidence of Parkinson's Disease, Amyotrophic Lateral Sclerosis, and Multiple System Atrophy in Chinese Populations.
Myasthenia Gravis
Association of myasthenia gravis with polymorphisms in the gene of histamine N-methyltransferase.
Neoplasms
Causal relationship between a tumour growth and the changes in histamine metabolism in tissues of sarcoma-bearing rat.
Neoplasms
Histamine and its metabolizing enzymes in tissues of primary ductal breast cancer.
Neoplasms
[A study on activity of beta-glucuronidase in serum and secretion from upper respiratory tract in patients with head and neck malignant tumors]
Parkinson Disease
Association Analyses of SNAP25, HNMT, FCHSD1, and DBH Single-Nucleotide Polymorphisms with Parkinson's Disease in a Northern Chinese Population.
Parkinson Disease
Association of Histamine N-Methyltransferase Thr105Ile Polymorphism with Parkinson's Disease and Schizophrenia in Han Chinese: A Case-Control Study.
Parkinson Disease
Determining the Effect of the HNMT, STK39, and NMD3 Polymorphisms on the Incidence of Parkinson's Disease, Amyotrophic Lateral Sclerosis, and Multiple System Atrophy in Chinese Populations.
Parkinson Disease
Histamine N-methyltransferase Thr105Ile is not associated with Parkinson's disease or essential tremor.
Parkinson Disease
Histamine N-methyltransferase Thr105Ile polymorphism is associated with Parkinson's disease.
Parkinson Disease
No association between histamine N-methyltransferase functional polymorphism Thr105Ile and Alzheimer's disease.
Parkinson Disease
The nonsynonymous Thr105Ile polymorphism of the histamine N-methyltransferase is associated to the risk of developing essential tremor.
Parkinson Disease
Thr105Ile (rs11558538) polymorphism in the histamine N-methyltransferase (HNMT) gene and risk for Parkinson disease: A PRISMA-compliant systematic review and meta-analysis.
Peptic Ulcer
Histamine and peptic ulcer disease: histamine methyltransferase activity in gastric mucosa of control subjects and duodenal ulcer patients before and after surgical treatment.
Pick Disease of the Brain
Human brain cytosolic histamine-N-methyltransferase is decreased in Down syndrome and increased in Pick's disease.
Rhinitis
Polymorphisms of histamine-metabolizing enzymes and clinical manifestations of asthma and allergic rhinitis.
Rhinitis, Allergic
Association of the histamine N-methyltransferase C314T (Thr105Ile) polymorphism with atopic dermatitis in Caucasian children.
Seizures
Differences in activity in cerebral methyltransferases and monoamine oxidases between audiogenic seizure susceptible and resistant mice and deermice.
Skin Diseases
Pathogenesis of lupus dermatoses in autoimmune mice. X. Evaluation of histamine-N-methyltransferase activity in the skin of autoimmune.
Stomach Ulcer
Single nucleotide polymorphisms and haplotypes of histamine N-methyltransferase in patients with gastric ulcer.
Synucleinopathies
Determining the Effect of the HNMT, STK39, and NMD3 Polymorphisms on the Incidence of Parkinson's Disease, Amyotrophic Lateral Sclerosis, and Multiple System Atrophy in Chinese Populations.
Tachycardia
Influence of SKF 91488, histamine N-methyltransferase inhibitor, on the central cardiovascular regulation during controlled, stepwise hemorrhagic hypotension in rats.
Tinnitus
Heidelberg Neuro-Music Therapy Enhances Task-Negative Activity in Tinnitus Patients.
Tinnitus
Heidelberg Neuro-Music Therapy Restores Attention-Related Activity in the Angular Gyrus in Chronic Tinnitus Patients.
Tremor
The nonsynonymous Thr105Ile polymorphism of the histamine N-methyltransferase is associated to the risk of developing essential tremor.
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