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IUBMB CommentsThe product reacts with water to form (S)-2-amino-6-oxohexanoate.
The enzyme appears in viruses and cellular organisms
Synonyms
l-pipecolate dehydrogenase,
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L-pipecolate + acceptor = (S)-2,3,4,5-tetrahydropyridine-2-carboxylate + reduced acceptor
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L-pipecolate:acceptor 1,6-oxidoreductase
The product reacts with water to form (S)-2-amino-6-oxohexanoate.
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L-pipecolate + acceptor
2,3,4,5-tetrahydropyridine-2-carboxylate + reduced acceptor
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acceptors: 2,6-dichlorophenolindophenol, redox dyes
product reacts with H2O to form 2-aminoadipate 6-semialdehyde, i.e. 2-amino-6-oxohexanoate
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Cu2+
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0.03 mM, 65% inhibition, 0.1 mM, 90% inhibition, 1 mM, 100% inhibition
p-chloromercuribenzoate
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7.4
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pipecolate + 2,6-dichlorophenolindophenol
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P2 ATCC 25571
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Q1QCC5_PSYCK
Psychrobacter cryohalolentis (strain ATCC BAA-1226 / DSM 17306 / VKM B-2378 / K5)
428
0
47094
TrEMBL
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G8Q4Y1_PSEO1
Pseudomonas ogarae (strain DSM 112162 / CECT 30235 / F113)
427
0
46413
TrEMBL
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A5WAX5_PSEP1
Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)
478
0
51550
TrEMBL
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Q1GES3_RUEST
Ruegeria sp. (strain TM1040)
432
0
46088
TrEMBL
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Baginsky, M.L.; Rodwell, V.W.
Metabolism of pipecolic acid in a Pseudomonas species. V. Pipecolate oxidase and dehydrogenase
J. Bacteriol.
94
1034-1039
1967
Pseudomonas putida
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