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Information on EC 1.2.1.73 - sulfoacetaldehyde dehydrogenase

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EC Tree
IUBMB Comments
This reaction is part of a bacterial pathway that can utilize the amino group of taurine as a sole source of nitrogen for growth. At physiological concentrations, NAD+ cannot be replaced by NADP+. The enzyme is specific for sulfoacetaldehyde, as formaldehyde, acetaldehyde, betaine aldehyde, propanal, glyceraldehyde, phosphonoacetaldehyde, glyoxylate, glycolaldehyde and 2-oxobutyrate are not substrates.
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The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
sulfoacetaldehyde dehydrogenase, nad-coupled sulfoacetaldehyde dehydrogenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-sulfoacetaldehyde + H2O + NAD+ = sulfoacetate + NADH + 2 H+
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PATHWAY SOURCE
PATHWAYS
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